Synergistic Apoptosis-Inducing Antileukemic Effects of Arsenic Trioxide and Mucuna macrocarpa Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism

The objective of this study was to examine the potential of enhancing the antileukemic activity of arsenic trioxide (ATO) by combining it with a folk remedy, crude methanolic extract of Mucuna macrocarpa (CMEMM). Human leukemia cells HL-60, Jurkat, and Molt-3 were treated with various doses of ATO,...

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Detalles Bibliográficos
Autores principales: Lu, Kuan-Hung, Lee, Hui-Ju, Huang, Min-Li, Lai, Shang-Chih, Ho, Yu-Ling, Chang, Yuan-Shiun, Chi, Chin-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150200/
https://www.ncbi.nlm.nih.gov/pubmed/21826188
http://dx.doi.org/10.1155/2012/921430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150200/
https://www.ncbi.nlm.nih.gov/pubmed/21826188
http://dx.doi.org/10.1155/2012/921430

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