Simple isatin derivatives as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship

To develop more potent small molecules with enhanced free radical scavenger properties, a series of N-substituted isatin derivatives was synthesized, and the cytoprotective effect on the apoptosis of PC12 cells induced by H(2)O(2 )was screened. All these compounds were found to be active, and N-ethy...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Wang, Ye, Hao, Xiaojiang, Mu, Shuzhen, Sun, Qianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150235/
https://www.ncbi.nlm.nih.gov/pubmed/21722377
http://dx.doi.org/10.1186/1752-153X-5-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150235/
https://www.ncbi.nlm.nih.gov/pubmed/21722377
http://dx.doi.org/10.1186/1752-153X-5-37

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