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Simple isatin derivatives as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship
To develop more potent small molecules with enhanced free radical scavenger properties, a series of N-substituted isatin derivatives was synthesized, and the cytoprotective effect on the apoptosis of PC12 cells induced by H(2)O(2 )was screened. All these compounds were found to be active, and N-ethy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150235/ https://www.ncbi.nlm.nih.gov/pubmed/21722377 http://dx.doi.org/10.1186/1752-153X-5-37 |