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Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments
BACKGROUND: TILLING (Targeting induced local lesions IN genomes) is an efficient reverse genetics approach for detecting induced mutations in pools of individuals. Combined with the high-throughput of next-generation sequencing technologies, and the resolving power of overlapping pool design, TILLIN...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150297/ https://www.ncbi.nlm.nih.gov/pubmed/21756356 http://dx.doi.org/10.1186/1471-2105-12-287 |