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Cancer-induced bone pain sequentially activates the ERK/MAPK pathway in different cell types in the rat spinal cord
BACKGROUND: Previous studies have demonstrates that, after nerve injury, extracellular signal-regulated protein kinase (ERK) activation in the spinal cord-initially in neurons, then microglia, and finally astrocytes. In addition, phosphorylation of ERK (p-ERK) contributes to nociceptive responses fo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150304/ https://www.ncbi.nlm.nih.gov/pubmed/21722369 http://dx.doi.org/10.1186/1744-8069-7-48 |