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Cancer-induced bone pain sequentially activates the ERK/MAPK pathway in different cell types in the rat spinal cord

BACKGROUND: Previous studies have demonstrates that, after nerve injury, extracellular signal-regulated protein kinase (ERK) activation in the spinal cord-initially in neurons, then microglia, and finally astrocytes. In addition, phosphorylation of ERK (p-ERK) contributes to nociceptive responses fo...

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Detalles Bibliográficos
Autores principales: Wang, Li-na, Yao, Ming, Yang, Jian-ping, Peng, Jun, Peng, Yan, Li, Cai-fang, Zhang, Yan-bing, Ji, Fu-hai, Cheng, Hao, Xu, Qi-nian, Wang, Xiu-yun, Zuo, Jian-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150304/
https://www.ncbi.nlm.nih.gov/pubmed/21722369
http://dx.doi.org/10.1186/1744-8069-7-48