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Choice of population structure informative principal components for adjustment in a case-control study

BACKGROUND: There are many ways to perform adjustment for population structure. It remains unclear what the optimal approach is and whether the optimal approach varies by the type of samples and substructure present. The simplest and most straightforward approach is to adjust for the continuous prin...

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Detalles Bibliográficos
Autores principales: Peloso, Gina M, Lunetta, Kathryn L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150322/
https://www.ncbi.nlm.nih.gov/pubmed/21771328
http://dx.doi.org/10.1186/1471-2156-12-64