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Choice of population structure informative principal components for adjustment in a case-control study
BACKGROUND: There are many ways to perform adjustment for population structure. It remains unclear what the optimal approach is and whether the optimal approach varies by the type of samples and substructure present. The simplest and most straightforward approach is to adjust for the continuous prin...
Autores principales: | Peloso, Gina M, Lunetta, Kathryn L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150322/ https://www.ncbi.nlm.nih.gov/pubmed/21771328 http://dx.doi.org/10.1186/1471-2156-12-64 |
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