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Role of tissue transglutaminase 2 in the acquisition of a mesenchymal-like phenotype in highly invasive A431 tumor cells

BACKGROUND: Cancer progression is closely linked to the epithelial-mesenchymal transition (EMT) process. Studies have shown that there is increased expression of tissue tranglutaminase (TG2) in advanced invasive cancer cells. TG2 catalyzes the covalent cross-linking of proteins, exhibits G protein a...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Yu, Tsai, Pei-Hsun, Kandaswami, Chithan C, Chang, Geen-Dong, Cheng, Chia-Hsiung, Huang, Chang-Jen, Lee, Ping-Ping, Hwang, Jiuan-Jiuan, Lee, Ming-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150327/
https://www.ncbi.nlm.nih.gov/pubmed/21777419
http://dx.doi.org/10.1186/1476-4598-10-87