Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems

BACKGROUND: The CRISPR-Cas adaptive immunity systems that are present in most Archaea and many Bacteria function by incorporating fragments of alien genomes into specific genomic loci, transcribing the inserts and using the transcripts as guide RNAs to destroy the genome of the cognate virus or plas...

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Detalles Bibliográficos
Autores principales: Makarova, Kira S, Aravind, L, Wolf, Yuri I, Koonin, Eugene V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150331/
https://www.ncbi.nlm.nih.gov/pubmed/21756346
http://dx.doi.org/10.1186/1745-6150-6-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150331/
https://www.ncbi.nlm.nih.gov/pubmed/21756346
http://dx.doi.org/10.1186/1745-6150-6-38

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