TAT-Mediated Transduction of MafA Protein In Utero Results in Enhanced Pancreatic Insulin Expression and Changes in Islet Morphology

Alongside Pdx1 and Beta2/NeuroD, the transcription factor MafA has been shown to be instrumental in the maintenance of the beta cell phenotype. Indeed, a combination of MafA, Pdx1 and Ngn3 (an upstream regulator of Beta2/NeuroD) was recently reported to lead to the effective reprogramming of acinar...

Descripción completa

Detalles Bibliográficos
Autores principales: Vargas, Nancy, Álvarez-Cubela, Silvia, Giraldo, Jaime A., Nieto, Margarita, Fort, Nicholas M., Cechin, Sirlene, García, Enrique, Espino-Grosso, Pedro, Fraker, Christopher A., Ricordi, Camillo, Inverardi, Luca, Pastori, Ricardo L., Domínguez-Bendala, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150355/
https://www.ncbi.nlm.nih.gov/pubmed/21857924
http://dx.doi.org/10.1371/journal.pone.0022364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150355/
https://www.ncbi.nlm.nih.gov/pubmed/21857924
http://dx.doi.org/10.1371/journal.pone.0022364

Ejemplares similares