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ISL1 Promotes Pancreatic Islet Cell Proliferation

BACKGROUND: Islet 1 (ISL1), a LIM-homeodomain transcription factor is essential for promoting pancreatic islets proliferation and maintaining endocrine cells survival in embryonic and postnatal pancreatic islets. However, how ISL1 exerts the role in adult islets is, to date, not clear. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Guo, Ting, Wang, Weiping, Zhang, Hui, Liu, Yinan, Chen, Ping, Ma, Kangtao, Zhou, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150357/
https://www.ncbi.nlm.nih.gov/pubmed/21829621
http://dx.doi.org/10.1371/journal.pone.0022387