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Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells
BACKGROUND: Autocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine signaling via fibroblast growth factor-4 (FGF4) is known to be required in mouse ESC (mESC) ne...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150375/ https://www.ncbi.nlm.nih.gov/pubmed/21829665 http://dx.doi.org/10.1371/journal.pone.0022892 |