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Modulation of Androgen Receptor Signaling in Hormonal Therapy-Resistant Prostate Cancer Cell Lines

BACKGROUND: Prostate epithelial cells depend on androgens for survival and function. In (early) prostate cancer (PCa) androgens also regulate tumor growth, which is exploited by hormonal therapies in metastatic disease. The aim of the present study was to characterize the androgen receptor (AR) resp...

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Detalles Bibliográficos
Autores principales: Marques, Rute B., Dits, Natasja F., Erkens-Schulze, Sigrun, van IJcken, Wilfred F. J., van Weerden, Wytske M., Jenster, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150397/
https://www.ncbi.nlm.nih.gov/pubmed/21829708
http://dx.doi.org/10.1371/journal.pone.0023144