Differential Inhibitor Sensitivity between Human Kinases VRK1 and VRK2

Human vaccinia-related kinases (VRK1 and VRK2) are atypical active Ser-Thr kinases implicated in control of cell cycle entry, apoptosis and autophagy, and affect signalling by mitogen activated protein kinases (MAPK). The specific structural differences in VRK catalytic sites make them suitable cand...

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Detalles Bibliográficos
Autores principales: Vázquez-Cedeira, Marta, Barcia-Sanjurjo, Iria, Sanz-García, Marta, Barcia, Ramiro, Lazo, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150407/
https://www.ncbi.nlm.nih.gov/pubmed/21829721
http://dx.doi.org/10.1371/journal.pone.0023235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150407/
https://www.ncbi.nlm.nih.gov/pubmed/21829721
http://dx.doi.org/10.1371/journal.pone.0023235

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