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Mitochondrial Network Determines Intracellular ROS Dynamics and Sensitivity to Oxidative Stress through Switching Inter-Mitochondrial Messengers

Oxidative stresses caused by reactive oxygen species (ROS) can induce rapid depolarization of inner mitochondrial membrane potential and subsequent impairment of oxidative phosphorylation. Damaged mitochondria produce more ROS, especially the superoxide anion (O(2) (−)) and hydrogen peroxide (H(2)O(...

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Detalles Bibliográficos
Autores principales: Park, Junseong, Lee, Jungsul, Choi, Chulhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150422/
https://www.ncbi.nlm.nih.gov/pubmed/21829717
http://dx.doi.org/10.1371/journal.pone.0023211