Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

Plasmodium vivax and Plasmodium knowlesi depend on the Duffy-Binding Protein DBL domain (RII-PvDBP or RII-PkDBP) engaging Duffy Antigen/Receptor for Chemokines on red blood cells during invasion. Inhibition of this key interaction provides an excellent opportunity for parasite control. There are com...

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Detalles Bibliográficos
Autores principales: Batchelor, Joseph D., Zahm, Jacob A., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150435/
https://www.ncbi.nlm.nih.gov/pubmed/21743458
http://dx.doi.org/10.1038/nsmb.2088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150435/
https://www.ncbi.nlm.nih.gov/pubmed/21743458
http://dx.doi.org/10.1038/nsmb.2088

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