Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication

Some 30% of acute myeloid leukemia (AML) patients display an internal tandem duplication (ITD) mutation in the FMS-like tyrosine kinase 3 (FLT3) gene. FLT3-ITDs are known to drive hematopoietic stem cells towards FLT3 ligand independent growth, but the effects on dendritic cell (DC) differentiation...

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Detalles Bibliográficos
Autores principales: Rickmann, Mareike, Krauter, Juergen, Stamer, Kathrin, Heuser, Michael, Salguero, Gustavo, Mischak-Weissinger, Eva, Ganser, Arnold, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150660/
https://www.ncbi.nlm.nih.gov/pubmed/21520003
http://dx.doi.org/10.1007/s00277-011-1231-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150660/
https://www.ncbi.nlm.nih.gov/pubmed/21520003
http://dx.doi.org/10.1007/s00277-011-1231-2

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