Cargando…

Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication

Some 30% of acute myeloid leukemia (AML) patients display an internal tandem duplication (ITD) mutation in the FMS-like tyrosine kinase 3 (FLT3) gene. FLT3-ITDs are known to drive hematopoietic stem cells towards FLT3 ligand independent growth, but the effects on dendritic cell (DC) differentiation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rickmann, Mareike, Krauter, Juergen, Stamer, Kathrin, Heuser, Michael, Salguero, Gustavo, Mischak-Weissinger, Eva, Ganser, Arnold, Stripecke, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150660/ https://www.ncbi.nlm.nih.gov/pubmed/21520003 http://dx.doi.org/10.1007/s00277-011-1231-2

Ejemplares similares

Monitoring dendritic cell and cytokine biomarkers during remission prior to relapse in patients with FLT3-ITD acute myeloid leukemia
por: Rickmann, Mareike, et al.
Publicado: (2013)

Prognostic Value of FLT3-Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia
por: Grob, Tim, et al.
Publicado: (2023)

Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis
por: Hellesøy, Monica, et al.
Publicado: (2021)

Frequency of FLT3 Internal Tandem Duplications in Adult Syrian Patients with Acute Myeloid Leukemia and Normal Karyotype
por: Al-Arbeed, Ismael F, et al.
Publicado: (2021)

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia
por: Bibault, Jean-Emmanuel, et al.
Publicado: (2015)

S135: NEXT-GENERATION SEQUENCING-BASED MEASURABLE RESIDUAL DISEASE MONITORING IN ACUTE MYELOID LEUKEMIA WITH FLT3 INTERNAL TANDEM DUPLICATION TREATED WITH INTENSIVE CHEMOTHERAPY PLUS MIDOSTAURIN
por: Rücker, Frank G, et al.
Publicado: (2023)

Prognostic significance of nucleophosmin mutations and FLT3 internal tandem duplication in adult patients with cytogenetically normal acute myeloid leukemia
por: Kim, Yeo-Kyeoung, et al.
Publicado: (2010)

Midostaurin after allogeneic stem cell transplant in patients with FLT3-internal tandem duplication-positive acute myeloid leukemia
por: Maziarz, Richard T., et al.
Publicado: (2020)

Minor BCR-ABL1-Positive Acute Myeloid Leukemia Associated With the NPM1 Mutation and FLT3 Internal Tandem Duplication
por: Kim, Moon Jung, et al.
Publicado: (2016)

Combined Expression of CD34 and FLT3-Internal Tandem Duplication Mutation Predicts Poor Response to Treatment in Acute Myeloid Leukemia
por: Abdellateif, Mona S, et al.
Publicado: (2020)

Association of FLT3-internal tandem duplication length with overall survival in acute myeloid leukemia: a systematic review and meta-analysis
por: Polak, Tobias B., et al.
Publicado: (2022)

Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia
por: Straube, Jasmin, et al.
Publicado: (2023)

Persistence of UBTF tandem duplications in remission in acute myeloid leukaemia
por: Harrop, Sean, et al.
Publicado: (2023)

Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models
por: Mali, Raghuveer Singh, et al.
Publicado: (2020)

Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia
por: Lee, Hyo Jeong, et al.
Publicado: (2017)

Characterization of FLT3-ITD(mut) acute myeloid leukemia: molecular profiling of leukemic precursor cells
por: Travaglini, Serena, et al.
Publicado: (2020)

Myeloid and Plasmacytoid Dendritic Cells and Cancer – New Insights
por: Gulubova, Maya
Publicado: (2019)

Plasmacytoid Dendritic Cell Infiltration in Acute Myeloid Leukemia
por: Zhu, Lidan, et al.
Publicado: (2020)

Pim-1 Kinase Phosphorylates and Stabilizes 130 kDa FLT3 and Promotes Aberrant STAT5 Signaling in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication
por: Natarajan, Karthika, et al.
Publicado: (2013)

Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications
por: Döhner, Hartmut, et al.
Publicado: (2022)

Blastic Plasmacytoid Dendritic Cell Neoplasm with Leukemic Component
por: Esteso, Maria Jimenez
Publicado: (2019)

Soluble Flt-1 Gene Delivery in Acute Myeloid Leukemic Cells Mediating a Nonviral Gene Carrier
por: Amini, Razieh, et al.
Publicado: (2013)

Correction: Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia
por: Lee, Hyo Jeong, et al.
Publicado: (2018)

Reply to the Comment on Association of FLT3-internal tandem duplication length with overall survival in acute myeloid leukemia: a systematic review and meta-analysis
por: Polak, Tobias B., et al.
Publicado: (2022)

Plasmacytoid Dendritic Cells Proliferation Coexisted with Acute Myeloid Leukemia
por: Wang, Min, et al.
Publicado: (2018)

Plasmacytoid Dendritic Cells, a Novel Target in Myeloid Neoplasms
por: Roussel, Xavier, et al.
Publicado: (2022)

Detection of NPM1 exon 12 mutations and FLT3 – internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia
por: Tan, Angela YC, et al.
Publicado: (2008)

FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm
por: Kim, Borahm, et al.
Publicado: (2019)

Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia
por: Latuske, Emily-Marie, et al.
Publicado: (2017)

Circulating myeloid and plasmacytoid dendritic cells are strongly diminished in septic shock
por: Grimaldi, David, et al.
Publicado: (2008)

Quercetin Administration Suppresses the Cytokine Storm in Myeloid and Plasmacytoid Dendritic Cells
por: Verna, Giulio, et al.
Publicado: (2021)

P1262: GILTERITINIB MAINTENANCE AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR RELAPSED/REFRACTORY ACUTE MYELOID LEUKEMIA WITH FLT3–INTERNAL TANDEM DUPLICATION MUTATION
por: Liang, Chen, et al.
Publicado: (2023)

Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD)
por: Sun, Q-Y, et al.
Publicado: (2017)

Targeting BRD4 in acute myeloid leukemia with partial tandem duplication of the MLL gene
por: Bill, Marius, et al.
Publicado: (2021)

Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis
por: He, Rong, et al.
Publicado: (2019)

FLT3 inhibitors in acute myeloid leukemia
por: Wu, Mei, et al.
Publicado: (2018)

Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition
por: Tel, Jurjen, et al.
Publicado: (2016)

Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma
por: Chevolet, Ines, et al.
Publicado: (2015)

Immunophenotypic and Molecular Features of Acute Myeloid Leukemia with Plasmacytoid Dendritic Cell Differentiation Are Distinct from Blastic Plasmacytoid Dendritic Cell Neoplasm
por: Wang, Wei, et al.
Publicado: (2022)

Correction to: Hybridization capture-based next-generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis
por: He, Rong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ffr7r9t3jn3nkhq3ak8kk3pege