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Global Identification of SMAD2 Target Genes Reveals a Role for Multiple Co-regulatory Factors in Zebrafish Early Gastrulas

Nodal and Smad2/3 signals play pivotal roles in mesendoderm induction and axis determination during late blastulation and early gastrulation in vertebrate embryos. However, Smad2/3 direct target genes during those critical developmental stages have not been systematically identified. Here, through C...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoting, Lin, Xiwen, Cai, Zhaoping, Zhang, Zhuqiang, Han, Chunsheng, Jia, Shunji, Meng, Anming, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151094/
https://www.ncbi.nlm.nih.gov/pubmed/21669877
http://dx.doi.org/10.1074/jbc.M111.236307