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Vesicle-associated Membrane Protein-2 (VAMP2) Mediates cAMP-stimulated Renin Release in Mouse Juxtaglomerular Cells

Renin is essential for blood pressure control. Renin is stored in granules in juxtaglomerular (JG) cells, located in the pole of the renal afferent arterioles. The second messenger cAMP stimulates renin release. However, it is unclear whether fusion and exocytosis of renin-containing granules is inv...

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Detalles Bibliográficos
Autores principales: Mendez, Mariela, Gross, Kenneth W., Glenn, Sean T., Garvin, Jeffrey L., Carretero, Oscar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151102/
https://www.ncbi.nlm.nih.gov/pubmed/21708949
http://dx.doi.org/10.1074/jbc.M111.225839