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Vesicle-associated Membrane Protein-2 (VAMP2) Mediates cAMP-stimulated Renin Release in Mouse Juxtaglomerular Cells
Renin is essential for blood pressure control. Renin is stored in granules in juxtaglomerular (JG) cells, located in the pole of the renal afferent arterioles. The second messenger cAMP stimulates renin release. However, it is unclear whether fusion and exocytosis of renin-containing granules is inv...
Autores principales: | Mendez, Mariela, Gross, Kenneth W., Glenn, Sean T., Garvin, Jeffrey L., Carretero, Oscar A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151102/ https://www.ncbi.nlm.nih.gov/pubmed/21708949 http://dx.doi.org/10.1074/jbc.M111.225839 |
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