Predicting a small molecule-kinase interaction map: A machine learning approach

BACKGROUND: We present a machine learning approach to the problem of protein ligand interaction prediction. We focus on a set of binding data obtained from 113 different protein kinases and 20 inhibitors. It was attained through ATP site-dependent binding competition assays and constitutes the first...

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Detalles Bibliográficos
Autores principales: Buchwald, Fabian, Richter, Lothar, Kramer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151211/
https://www.ncbi.nlm.nih.gov/pubmed/21708012
http://dx.doi.org/10.1186/1758-2946-3-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151211/
https://www.ncbi.nlm.nih.gov/pubmed/21708012
http://dx.doi.org/10.1186/1758-2946-3-22

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