Detection of autoreactive CD4 T cells using major histocompatibility complex class II dextramers

BACKGROUND: Tetramers are useful tools to enumerate the frequencies of antigen-specific T cells. However, unlike CD8 T cells, CD4 T cells - especially self-reactive cells - are challenging to detect with major histocompatibility complex (MHC) class II tetramers because of low frequencies and low aff...

Descripción completa

Detalles Bibliográficos
Autores principales: Massilamany, Chandirasegaran, Upadhyaya, Bijaya, Gangaplara, Arunakumar, Kuszynski, Charles, Reddy, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151213/
https://www.ncbi.nlm.nih.gov/pubmed/21767394
http://dx.doi.org/10.1186/1471-2172-12-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151213/
https://www.ncbi.nlm.nih.gov/pubmed/21767394
http://dx.doi.org/10.1186/1471-2172-12-40

Ejemplares similares