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Hydroxylation of recombinant human collagen type I alpha 1 in transgenic maize co-expressed with a recombinant human prolyl 4-hydroxylase

BACKGROUND: Collagens require the hydroxylation of proline (Pro) residues in their triple-helical domain repeating sequence Xaa-Pro-Gly to function properly as a main structural component of the extracellular matrix in animals at physiologically relevant conditions. The regioselective proline hydrox...

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Detalles Bibliográficos
Autores principales: Xu, Xing, Gan, Qinglei, Clough, Richard C, Pappu, Kameshwari M, Howard, John A, Baez, Julio A, Wang, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151215/
https://www.ncbi.nlm.nih.gov/pubmed/21702901
http://dx.doi.org/10.1186/1472-6750-11-69