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Hydroxylation of recombinant human collagen type I alpha 1 in transgenic maize co-expressed with a recombinant human prolyl 4-hydroxylase
BACKGROUND: Collagens require the hydroxylation of proline (Pro) residues in their triple-helical domain repeating sequence Xaa-Pro-Gly to function properly as a main structural component of the extracellular matrix in animals at physiologically relevant conditions. The regioselective proline hydrox...
Autores principales: | Xu, Xing, Gan, Qinglei, Clough, Richard C, Pappu, Kameshwari M, Howard, John A, Baez, Julio A, Wang, Kan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151215/ https://www.ncbi.nlm.nih.gov/pubmed/21702901 http://dx.doi.org/10.1186/1472-6750-11-69 |
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