HIV Envelope gp120 Activates LFA-1 on CD4 T-Lymphocytes and Increases Cell Susceptibility to LFA-1-Targeting Leukotoxin (LtxA)

The cellular adhesion molecule LFA-1 and its ICAM-1 ligand play an important role in promoting HIV-1 infectivity and transmission. These molecules are present on the envelope of HIV-1 virions and are integral components of the HIV virological synapse. However, cellular activation is required to conv...

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Detalles Bibliográficos
Autores principales: Hioe, Catarina E., Tuen, Michael, Vasiliver-Shamis, Gaia, Alvarez, Yelina, Prins, Kathleen C., Banerjee, Sagarika, Nádas, Arthur, Cho, Michael W., Dustin, Michael L., Kachlany, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151267/
https://www.ncbi.nlm.nih.gov/pubmed/21850260
http://dx.doi.org/10.1371/journal.pone.0023202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151267/
https://www.ncbi.nlm.nih.gov/pubmed/21850260
http://dx.doi.org/10.1371/journal.pone.0023202

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