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Genome-Wide Screening for Genes Associated with FK506 Sensitivity in Fission Yeast

We have been studying calcineurin signal transduction pathway in fission yeast Schizosaccharomyces pombe (S. pombe) by developing a genetic screen for mutants that show hypersensitivity to the immunosuppressive calcineurin inhibitor FK506 (tacrolimus). In the present study, to identify nonessential...

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Detalles Bibliográficos
Autores principales: Ma, Yan, Jiang, Weijuan, Liu, Qingbin, Ryuko, Sayomi, Kuno, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151288/
https://www.ncbi.nlm.nih.gov/pubmed/21850271
http://dx.doi.org/10.1371/journal.pone.0023422