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The Interaction of LFA-1 on Mononuclear Cells and ICAM-1 on Tubular Epithelial Cells Accelerates TGF-β1-Induced Renal Epithelial-Mesenchymal Transition

The epithelial-mesenchymal transition (EMT) of renal epithelial cells (RTECs) has pivotal roles in the development of renal fibrosis. Although the interaction of lymphocyte function-associated antigen 1 (LFA-1) on leukocytes and its ligand, intracellular adhesion molecule 1 (ICAM-1), plays essential...

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Detalles Bibliográficos
Autores principales: Morishita, Yoshiyuki, Watanabe, Minami, Nakazawa, Eiko, Ishibashi, Kenichi, Kusano, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151298/
https://www.ncbi.nlm.nih.gov/pubmed/21850266
http://dx.doi.org/10.1371/journal.pone.0023267