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Follicular regulatory T (Tfr) cells with dual Foxp3 and Bcl6 expression suppress germinal center reactions

Foxp3(+) regulatory T (T(reg)) cells suppress different types of immune responses to help maintain homeostasis in the body. How T(reg) cells regulate humoral immunity, including germinal center reactions, is unclear. Here we identify a subset of T(reg) cells expressing CXCR5 and Bcl6, and localized...

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Detalles Bibliográficos
Autores principales: Chung, Yeonseok, Tanaka, Shinya, Chu, Fuliang, Nurieva, Roza, Martinez, Gustavo J., Rawal, Seema, Wang, Yi-Hong, Lim, Ho Yong, Reynolds, Joseph M., Zhou, Xiao-hui, Fan, Hui-min, Liu, Zhong-ming, Neelapu, Sattva S., Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151340/
https://www.ncbi.nlm.nih.gov/pubmed/21785430
http://dx.doi.org/10.1038/nm.2426