Akt deficiency delays tumor progression, vascular invasion, and distant metastases in a murine model of thyroid cancer

Akt activation is common in progressive thyroid cancer. In breast cancer, Akt1 induced primary cancer growth, but is reported to inhibit metastasis in vivo in several model systems. In contrast, clinical and in vitro studies suggest a metastasis-promoting role for Akt1 in thyroid cancer. The goal of...

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Detalles Bibliográficos
Autores principales: Saji, Motoyasu, Narahara, Katsunura, McCarty, Samantha K., Vasko, Vasily V., La Perle, Krista M., Porter, Kyle, Jarjoura, David, Lu, Changxue, Cheng, Sheue-Yann, Ringel, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151477/
https://www.ncbi.nlm.nih.gov/pubmed/21532616
http://dx.doi.org/10.1038/onc.2011.136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151477/
https://www.ncbi.nlm.nih.gov/pubmed/21532616
http://dx.doi.org/10.1038/onc.2011.136

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