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Protection of SH-SY5Y Neuronal Cells from Glutamate-Induced Apoptosis by 3,6′-Disinapoyl Sucrose, a Bioactive Compound Isolated from Radix Polygala

The neuroprotective effects of 3,6′-disinapoyl sucrose (DISS) from Radix Polygala against glutamate-induced SH-SY5Y neuronal cells injury were evaluated in the present study. SH-SY5Y neuronal cells were pretreated with glutamate (8 mM) for 30 min followed by cotreatment with DISS for 12 h. Cell viab...

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Detalles Bibliográficos
Autores principales: Hu, Yuan, Li, Jie, Liu, Ping, Chen, Xu, Guo, Dai-Hong, Li, Qing-Shan, Rahman, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151496/
https://www.ncbi.nlm.nih.gov/pubmed/21836813
http://dx.doi.org/10.1155/2012/728342