Neurturin Evokes MAPK-Dependent Upregulation of Egr4 and KCC2 in Developing Neurons

The K-Cl cotransporter KCC2 plays a crucial role in the functional development of GABA(A)-mediated responses rendering GABA hyperpolarizing in adult neurons. We have previously shown that BDNF upregulates KCC2 in immature neurons through the transcription factor Egr4. The effect of BDNF on Egr4 and...

Descripción completa

Detalles Bibliográficos
Autores principales: Ludwig, Anastasia, Uvarov, Pavel, Pellegrino, Christophe, Thomas-Crusells, Judith, Schuchmann, Sebastian, Saarma, Mart, Airaksinen, Matti S., Rivera, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151499/
https://www.ncbi.nlm.nih.gov/pubmed/21837281
http://dx.doi.org/10.1155/2011/641248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151499/
https://www.ncbi.nlm.nih.gov/pubmed/21837281
http://dx.doi.org/10.1155/2011/641248

Ejemplares similares