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Insulin-Regulated Trafficking of GLUT4 Requires Ubiquitination

A major consequence of insulin binding its receptor on fat and muscle cells is translocation of the facilitative glucose transporter GLUT4 from an intracellular store to the cell surface where it serves to clear glucose from the bloodstream. Sorting of GLUT4 into its insulin-sensitive store requires...

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Detalles Bibliográficos
Autores principales: Lamb, Christopher A, McCann, Rebecca K, Stöckli, Jacqueline, James, David E, Bryant, Nia J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152195/
https://www.ncbi.nlm.nih.gov/pubmed/20854370
http://dx.doi.org/10.1111/j.1600-0854.2010.01113.x