A Phase IIA Randomized Clinical Trial of a Multiclade HIV-1 DNA Prime Followed by a Multiclade rAd5 HIV-1 Vaccine Boost in Healthy Adults (HVTN204)

BACKGROUND: The safety and immunogenicity of a vaccine regimen consisting of a 6-plasmid HIV-1 DNA prime (envA, envB, envC, gagB, polB, nefB) boosted by a recombinant adenovirus serotype-5 (rAd5) HIV-1 with matching inserts was evaluated in HIV-seronegative participants from South Africa, United Sta...

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Detalles Bibliográficos
Autores principales: Churchyard, Gavin J., Morgan, Cecilia, Adams, Elizabeth, Hural, John, Graham, Barney S., Moodie, Zoe, Grove, Doug, Gray, Glenda, Bekker, Linda-Gail, McElrath, M. Juliana, Tomaras, Georgia D., Goepfert, Paul, Kalams, Spyros, Baden, Lindsey R., Lally, Michelle, Dolin, Raphael, Blattner, William, Kalichman, Artur, Figueroa, J. Peter, Pape, Jean, Schechter, Mauro, Defawe, Olivier, De Rosa, Stephen C., Montefiori, David C., Nabel, Gary J., Corey, Lawrence, Keefer, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152265/
https://www.ncbi.nlm.nih.gov/pubmed/21857901
http://dx.doi.org/10.1371/journal.pone.0021225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152265/
https://www.ncbi.nlm.nih.gov/pubmed/21857901
http://dx.doi.org/10.1371/journal.pone.0021225

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