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High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing

Human cells are constantly exposed to environmental and endogenous agents which can induce damage to DNA. Understanding the implications of these DNA modifications in the etiology of human diseases requires the examination about how these DNA lesions block DNA replication and induce mutations in cel...

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Detalles Bibliográficos
Autores principales:	Yuan, Bifeng, Wang, Jianshuang, Cao, Huachuan, Sun, Ruobai, Wang, Yinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152323/ https://www.ncbi.nlm.nih.gov/pubmed/21470959 http://dx.doi.org/10.1093/nar/gkr159

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