Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant

Catechol-O-methyltransferase (COMT) is a major enzyme controlling catecholamine levels that plays a central role in cognition, affective mood and pain perception. There are three common COMT haplotypes in the human population reported to have functional effects, divergent in two synonymous and one n...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsao, Douglas, Shabalina, Svetlana A., Gauthier, Josée, Dokholyan, Nikolay V., Diatchenko, Luda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152328/
https://www.ncbi.nlm.nih.gov/pubmed/21486747
http://dx.doi.org/10.1093/nar/gkr165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152328/
https://www.ncbi.nlm.nih.gov/pubmed/21486747
http://dx.doi.org/10.1093/nar/gkr165

Ejemplares similares