The origin of genetic instability in CCTG repeats

CCTG tetranucleotide repeat expansion is associated with a hereditary neurological disease called myotonic dystrophy type 2 (DM2). The underlying reasons that lead to genetic instability and thus repeat expansion during DNA replication remains elusive. Here, we have shown CCTG repeats have a high pr...

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Detalles Bibliográficos
Autores principales: Lam, Sik Lok, Wu, Feng, Yang, Hao, Chi, Lai Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152338/
https://www.ncbi.nlm.nih.gov/pubmed/21478167
http://dx.doi.org/10.1093/nar/gkr185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152338/
https://www.ncbi.nlm.nih.gov/pubmed/21478167
http://dx.doi.org/10.1093/nar/gkr185

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