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The origin of genetic instability in CCTG repeats
CCTG tetranucleotide repeat expansion is associated with a hereditary neurological disease called myotonic dystrophy type 2 (DM2). The underlying reasons that lead to genetic instability and thus repeat expansion during DNA replication remains elusive. Here, we have shown CCTG repeats have a high pr...
Autores principales: | Lam, Sik Lok, Wu, Feng, Yang, Hao, Chi, Lai Man |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152338/ https://www.ncbi.nlm.nih.gov/pubmed/21478167 http://dx.doi.org/10.1093/nar/gkr185 |
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