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Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice
Dominant mutations in the rhodopsin gene, which is expressed in rod photoreceptor cells, are a major cause of the hereditary-blinding disease, autosomal dominant retinitis pigmentosa. Therapeutic strategies designed to edit such mutations will likely depend on the introduction of double-strand break...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152346/ https://www.ncbi.nlm.nih.gov/pubmed/21478169 http://dx.doi.org/10.1093/nar/gkr196 |