Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization

Mediator is a multiprotein co-activator of RNA polymerase (Pol) II transcription. Mediator contains a conserved core that comprises the ‘head’ and ‘middle’ modules. We present here a structure–function analysis of the essential Med11/22 heterodimer, a part of the head module. Med11/22 forms a conser...

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Detalles Bibliográficos
Autores principales: Seizl, Martin, Larivière, Laurent, Pfaffeneder, Toni, Wenzeck, Larissa, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152362/
https://www.ncbi.nlm.nih.gov/pubmed/21498544
http://dx.doi.org/10.1093/nar/gkr229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152362/
https://www.ncbi.nlm.nih.gov/pubmed/21498544
http://dx.doi.org/10.1093/nar/gkr229

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