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Tiotropium reduces risk of exacerbations irrespective of previous use of inhaled anticholinergics in placebo-controlled clinical trials

BACKGROUND: Data have highlighted the potential bias introduced by withdrawal of inhaled corticosteroids at randomization in chronic obstructive pulmonary disease trials examining inhaled corticosteroids. Analyses were conducted to determine whether this was true of inhaled anticholinergic withdrawa...

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Detalles Bibliográficos
Autores principales: Cooper, Christopher B, Anzueto, Antonio, Decramer, Marc, Celli, Bartolome, Tashkin, Donald P, Leimer, Inge, Kesten, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152465/
https://www.ncbi.nlm.nih.gov/pubmed/21845038
http://dx.doi.org/10.2147/COPD.S17864