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New tumor-targeted nanosized delivery carrier for oligonucleotides: characteristics in vitro and in vivo

BACKGROUND: The purpose of this study was to investigate the in vitro and in vivo characteristics of a new tumor-targeted nanosized delivery carrier for antisense oligonucleotide (ASON). METHODS: Polyethylenimine (PEI) was used to condense ASON to form nanosized complexes (PEI/ASON), which were then...

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Detalles Bibliográficos
Autores principales: Zhou, Tianyang, Jia, Xin, Li, Huixiang, Wang, Jin, Zhang, Hongling, A, Youmei, Zhang, Zhenzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152470/
https://www.ncbi.nlm.nih.gov/pubmed/21845042
http://dx.doi.org/10.2147/IJN.S15239