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New tumor-targeted nanosized delivery carrier for oligonucleotides: characteristics in vitro and in vivo
BACKGROUND: The purpose of this study was to investigate the in vitro and in vivo characteristics of a new tumor-targeted nanosized delivery carrier for antisense oligonucleotide (ASON). METHODS: Polyethylenimine (PEI) was used to condense ASON to form nanosized complexes (PEI/ASON), which were then...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152470/ https://www.ncbi.nlm.nih.gov/pubmed/21845042 http://dx.doi.org/10.2147/IJN.S15239 |