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Integrated Proteomic and Transcriptomic Investigation of the Acetaminophen Toxicity in Liver Microfluidic Biochip

Microfluidic bioartificial organs allow the reproduction of in vivo-like properties such as cell culture in a 3D dynamical micro environment. In this work, we established a method and a protocol for performing a toxicogenomic analysis of HepG2/C3A cultivated in a microfluidic biochip. Transcriptomic...

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Detalles Bibliográficos
Autores principales: Prot, Jean Matthieu, Briffaut, Anne-Sophie, Letourneur, Franck, Chafey, Philippe, Merlier, Franck, Grandvalet, Yves, Legallais, Cécile, Leclerc, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152546/
https://www.ncbi.nlm.nih.gov/pubmed/21857903
http://dx.doi.org/10.1371/journal.pone.0021268