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Integrated Proteomic and Transcriptomic Investigation of the Acetaminophen Toxicity in Liver Microfluidic Biochip
Microfluidic bioartificial organs allow the reproduction of in vivo-like properties such as cell culture in a 3D dynamical micro environment. In this work, we established a method and a protocol for performing a toxicogenomic analysis of HepG2/C3A cultivated in a microfluidic biochip. Transcriptomic...
Autores principales: | Prot, Jean Matthieu, Briffaut, Anne-Sophie, Letourneur, Franck, Chafey, Philippe, Merlier, Franck, Grandvalet, Yves, Legallais, Cécile, Leclerc, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152546/ https://www.ncbi.nlm.nih.gov/pubmed/21857903 http://dx.doi.org/10.1371/journal.pone.0021268 |
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