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High-Throughput Screening of Australian Marine Organism Extracts for Bioactive Molecules Affecting the Cellular Storage of Neutral Lipids

Mammalian cells store excess fatty acids as neutral lipids in specialised organelles called lipid droplets (LDs). Using a simple cell-based assay and open-source software we established a high throughput screen for LD formation in A431 cells in order to identify small bioactive molecules affecting l...

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Detalles Bibliográficos
Autores principales: Rae, James, Fontaine, Frank, Salim, Angela A., Lo, Harriet P., Capon, Robert J., Parton, Robert G., Martin, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152550/
https://www.ncbi.nlm.nih.gov/pubmed/21857959
http://dx.doi.org/10.1371/journal.pone.0022868