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Deletion of UCP2 in iNOS Deficient Mice Reduces the Severity of the Disease during Experimental Autoimmune Encephalomyelitis

Uncoupling protein 2 is a member of the mitochondrial anion carrier family that is widely expressed in neurons and the immune cells of humans. Deletion of Ucp2 gene in mice pre-activates the immune system leading to higher resistance toward infection and to an increased susceptibility to develop chr...

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Detalles Bibliográficos
Autores principales: Aheng, Caroline, Ly, Nathalie, Kelly, Mairead, Ibrahim, Saleh, Ricquier, Daniel, Alves-Guerra, Marie-Clotilde, Miroux, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152556/
https://www.ncbi.nlm.nih.gov/pubmed/21857957
http://dx.doi.org/10.1371/journal.pone.0022841