Predicting Transcriptional Activity of Multiple Site p53 Mutants Based on Hybrid Properties

As an important tumor suppressor protein, reactivate mutated p53 was found in many kinds of human cancers and that restoring active p53 would lead to tumor regression. In this work, we developed a new computational method to predict the transcriptional activity for one-, two-, three- and four-site p...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Niu, Shen, Xu, Zhongping, Huang, Yun, Kong, Xiangyin, Cai, Yu-Dong, Chou, Kuo-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152557/
https://www.ncbi.nlm.nih.gov/pubmed/21857971
http://dx.doi.org/10.1371/journal.pone.0022940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152557/
https://www.ncbi.nlm.nih.gov/pubmed/21857971
http://dx.doi.org/10.1371/journal.pone.0022940

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