Interaction of hnRNPA1/A2 and DAZAP1 with an Alu-Derived Intronic Splicing Enhancer Regulates ATM Aberrant Splicing

We have previously identified an Alu-derived Intronic Splicing enhancer (ISE) in the Ataxia Teleangectasia Mutated gene (ATM) that facilitates intron pre-mRNA processing and leads to the inclusion of a cryptic exon in the final mRNA transcript. By using an RNA pull-down assay, we show here that hnRN...

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Detalles Bibliográficos
Autores principales: Pastor, Tibor, Pagani, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152568/
https://www.ncbi.nlm.nih.gov/pubmed/21858080
http://dx.doi.org/10.1371/journal.pone.0023349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152568/
https://www.ncbi.nlm.nih.gov/pubmed/21858080
http://dx.doi.org/10.1371/journal.pone.0023349

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