Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts

BACKGROUND: Recent studies have demonstrated that activation of autophagy increases the lifespan of organisms from yeast to flies. In contrast to the lifespan extension effect in lower organisms, it has been reported that overexpression of unc-51-like kinase 3 (ULK3), the mammalian homolog of autoph...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Tae, Lee, Ki Baek, Kim, Sung Young, Choi, Hae Ri, Park, Sang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152578/
https://www.ncbi.nlm.nih.gov/pubmed/21858089
http://dx.doi.org/10.1371/journal.pone.0023367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152578/
https://www.ncbi.nlm.nih.gov/pubmed/21858089
http://dx.doi.org/10.1371/journal.pone.0023367

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