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Tumor necrosis factor-alpha (TNF-α) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes

BACKGROUND: We have shown functional expression of several TRP channels on human synovial cells, proposing significance in known calcium dependent proliferative and secretory responses in joint inflammation. The present study further characterizes synoviocyte TRP expression and activation responses...

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Detalles Bibliográficos
Autores principales: Kochukov, Mikhail Y, McNearney, Terry A, Yin, Huaizhi, Zhang, Liping, Ma, Fei, Ponomareva, Larissa, Abshire, Sarah, Westlund, Karin N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152771/
https://www.ncbi.nlm.nih.gov/pubmed/19695100
http://dx.doi.org/10.1186/1744-8069-5-49